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Collagen stimulators (biostimulators) are injectables that prompt your skin to produce its own collagen, rather than simply adding volume. They gradually improve firmness, support and skin quality. We work with Sculptra®, Radiesse®, HArmonyCa®, Juvelook® and Karisma®, and choose the right one for your skin and your goals.
Dr. Olga Gómez Montoya, a physician and surgeon trained at the University of Antioquia, uses them to support you through the passage of time with natural-looking results, without changing who you are.
Reviewed by Dr. Olga Gómez Montoya · Updated: October 2026
Original products registered with INVIMA (Colombia's national health products regulator) · Medical judgment
Over the years, and especially during menopause, the skin produces less collagen: it becomes thinner, loses firmness and the face loses support. A biostimulator is injected into or beneath the skin and activates fibroblasts, the cells that make collagen.
There are three main families:
During your medical assessment we decide which one is right for you, or whether none of them is.
It's not the right time if you're pregnant or breastfeeding, if you have an active infection in the area, or if you're looking for an immediate, dramatic change.
They gradually improve skin firmness, support and quality by stimulating your own collagen. They are especially helpful during menopause or after significant weight loss.
01
Helps improve the firmness of skin that has lost support over the years or with menopause, gradually and naturally. See non-surgical treatment for facial laxity.
02
Helps support the midface and temples without overdoing volume.
03
Provides support and firmness around the mouth and gradually softens the lines that run down from the corners of the mouth. See nasolabial folds and marionette lines.
04
Improves the definition of the facial oval and the transition to the neck, without changing your features. See facial harmonization.
05
Denser, more elastic and more even skin thanks to new collagen, especially when it thins during menopause. See skin quality.
06
Improves firmness and texture where the skin is thinner and the passage of time shows first. See neck and décolletage.
07
Arms, abdomen, buttocks and thighs, especially after significant weight loss or during menopause. See non-surgical buttock treatments and body treatments.
We choose the biostimulator based on your skin, the area and the type of laxity. They don't all do the same thing.
Stimulates collagen gradually. Useful for laxity and loss of support, including during menopause. Results become visible over 2 to 3 months. See Sculptra in Medellín.
Provide immediate support and stimulate collagen over time. When diluted, they improve the firmness of the neck, décolletage and body. See Radiesse in Medellín.
Combines an immediate support effect with progressive biostimulation in a single treatment. It is newer, and the evidence behind it is still being built.
Applied superficially to improve texture, pores, fine scars and radiance. It's the biostimulator we use around the eyes.
Larger particles placed deeper to provide gradual support in areas that have lost firmness.
Gradually improves skin quality, hydration and firmness without adding volume.
“The collagen your skin produces today is the firmness you'll notice in a few months.”
Dr. Olga Gómez Montoya is a physician and surgeon trained at the University of Antioquia, with a practice dedicated to aesthetic medicine in El Poblado, Medellín. She has performed more than 8,500 botulinum toxin, biostimulator and lip harmonization treatments, and more than 4,800 aesthetic technology procedures.
With collagen stimulators, we don't aim to change your features. We aim to give your skin support and quality, including during stages such as menopause, with an honest, progressive plan that respects your expression. We only use INVIMA-registered products from verified sources.
We review your skin, your facial structure, your medical history and what you want to achieve before recommending any procedure. If it's not right for you, we'll tell you. The assessment takes 30 to 45 minutes.
We choose the right biostimulator (Sculptra®, Radiesse®, Juvelook® or another) and determine how many sessions you might need. Usually 2 to 3, spaced weeks apart, because collagen builds up gradually.
Before we begin, we show you the product and its INVIMA registration. It's a 45- to 60-minute outpatient procedure with mild discomfort. You can return to your routine in 1 to 2 days, and we give you clear at-home care instructions, such as the massages some products require.
Results appear gradually and are usually visible within 2 to 3 months. We schedule two follow-up visits, at 15 and 30 days, to review your progress and adjust the plan. After that, maintenance is usually one session every two years, depending on your skin and your goals.
They are injectable treatments that prompt your skin to produce its own collagen. Instead of filling a specific spot, they gradually improve skin firmness, support and quality. The most widely used are poly-L-lactic acid (Sculptra®), calcium hydroxylapatite (Radiesse®) and hybrids with hyaluronic acid, such as HArmonyCa® or Juvelook®.
A hyaluronic acid filler provides immediate volume or definition in a specific spot. A biostimulator works on structure: it stimulates new collagen, and the result appears gradually. They are often combined.
There isn't one that's best for everyone. Sculptra® stimulates collagen gradually and has a long track record; Radiesse® provides immediate support plus biostimulation; HArmonyCa® combines hyaluronic acid and hydroxylapatite; Juvelook® works on skin quality and texture. We choose based on your skin, the area and what you want to achieve.
It depends on the biostimulator. With poly-L-lactic acid, the first changes are usually noticeable between the fourth and sixth week, and the result keeps building over the following 2 to 3 months. With calcium hydroxylapatite there is support from the start, which improves as your skin produces collagen. The effect lasts a long time and is usually maintained with one session every one to two years.
It depends on your skin, the degree of laxity and what you want to achieve. Typically it's 2 to 3 sessions at first, followed by maintenance. During your consultation, we'll define together the plan that best fits your needs and your budget.
Discomfort is usually mild, and you return to your routine in 1 to 2 days. Temporary swelling or bruising may occur. Some products require at-home massages, which we'll teach you. We schedule follow-up visits at 15 and 30 days.
The most common are swelling, bruising and tenderness for a few days. With poly-L-lactic acid, small papules or nodules may appear, which can almost always be felt more than seen; we minimize them with the right technique, dilution and massage. That's why we don't use them in the lips and we carefully choose the product for each area.
Yes, they are often a good option. Menopause speeds up the natural loss of collagen, and the skin becomes thinner and less firm. Collagen stimulators help your skin gradually produce new collagen. Whether they're right for you is confirmed during your medical assessment.
Yes. They are used to improve skin firmness on the arms, abdomen, buttocks, thighs, décolletage and hands, especially after weight loss or during menopause. They don't add volume the way an implant does. See non-surgical buttock treatments and hand rejuvenation.
It is not recommended during pregnancy or breastfeeding, with active infections in the area, with an allergy to any of the components, with certain active autoimmune diseases, or with a tendency toward abnormal scarring, such as keloids. That's why a medical assessment is essential.
The cost depends on the product, the area and the number of sessions you need. That's why we don't quote a one-size-fits-all price without assessing you first. At your consultation in El Poblado, we'll clearly explain your options and the investment involved. Book via WhatsApp.
Book a calm, unhurried consultation with no obligation, and decide with Dr. Olga Gómez whether collagen stimulators are right for you and which one suits you best.
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